Midway by way of his vocation, Cees Dekker reinvented himself. Just after several years of hardcore physics, he shifted his focus to ‘nanobiology’ with the convert of the millennium. A expression he coined himself, as being a make any difference of truth.
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Within the very same time, the group of Paul McEuen, who was then centered with the University of California, Berkeley, showed similar effects on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard College independently confirmed employing scanning tunnelling spectroscopy experiments.
Deposition and atomic pressure microscopy of specific phthalocyanine polymers amongst nanofabricated electrodes
2010, formulated a completely new way (‘wedging transfer’) to manipulate nanostructures; 1st report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores
Within the years following these discoveries, my research pursuits shifted to biophysics and nanobiology, And that i became significantly less associated with the development of nanotube electronics. The main target of many researchers in the sphere also shifted to graphene (wherever, funnily ample, the initial graphene ribbons had been called ‘nanotubes that happen to be Minimize open together their size’) right after the discovery of The 2-dimensional materials in 2004.
We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the basic function of spatial confinement for the molecular and mobile degree. Our initiatives include things like the following:
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
What if, in lieu of making use of conventional best-down silicon electronics, transistors could possibly be designed from The underside up using solitary organic molecules since the switching elements? This concept, which turned The idea of now’s discipline of molecular electronics, first emerged while in the nineteen seventies.
There was just one trouble though — we did not notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule degree, conducting polymers had been truly not these kinds of good conductors, which was somewhat disappointing. We So broadened our view to test to find more promising molecules.
‘The concept There exists this type of issue being a commencing, a huge bang, is cees dekker by now a fascinating signpost to consider that there was a creator. But more usually, and on the basis of pure rationality, I also get there at a Christian interpretation of truth. An atheistic worldview is really a naturalistic worldview: essentially, there are actually only atoms and natural forces that we are able to measure.
Afterwards we spoke again briefly simply because Dekker felt that our dialogue of his faith quickly grew to become purely philosophical, While it also concretely assists him in his work.
Visualization of unstained DNA nanostructures with advanced in-concentrate transmission electron microscopy approaches
The biophysicist from Delft – who is Just about the most cited scientists in the Netherlands For some time – can take his accountability to contribute to the rationalization and popularisation of his get the job done at the border of physics and biology exceptionally severely and often appears during the media; Otherwise to discuss his work, then about the connection among science and his Christian religion.